JPRN-UMIN000004296
Completed
未知
A phase II trial of gefitinib in combination with bevacizumab as first line therapy for advanced non-small-cell lung cancer with mutated EGFR - A phase II trial of gefitinib in combination with bevacizumab as first line therapy for advanced non-small-cell lung cancer with mutated EGFR
Okayama Lung Cancer Study Group0 sites42 target enrollmentOctober 1, 2010
Conditionsnon-small-cell lung cancer
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- non-small-cell lung cancer
- Sponsor
- Okayama Lung Cancer Study Group
- Enrollment
- 42
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1\. symptomatic brain metastasis 2\. pts with hemoptysis with 2\.5mL or more 3\. pts with radiological findings of tumor invasion to major vessels (i.e. aorta) and cavity lesion 4\. pts with bleeding tendency pts who need continuous use of antithrombotic agents 5\. candidate for curative radiation therapy 6\. have a history of severe drug allergy 7\. woman who is pregnant or wishing to become pregnant 8\. pts with massive pleural and cardiac effusion and ascites that need to be immediately treated 9\. pts with active co\-morbidities including severe conditions of heart diseases, infections, uncontrollable diabetes, uncontollable hypertension, interstitial pneumonia, active hepatitis and thrombotic disease.
Outcomes
Primary Outcomes
Not specified
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