Evaluation the safety efficacy bilaterally dosed topical lipoic acid cyclodexterin eye drops for the treatment presbyopia.

Phase 2

• Conditions: Presbyopia.; Accommodation and refraction; H49-H52

• Registration Number: IRCT20181215041972N1
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 25 March 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

BCDVA of 20/20
DCNVA worsen than 20/40 in each eye
Age 40-55 years old

Exclusion Criteria

Without any underlying disease

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Evaluation of efficacy and side effect of lipoic acid eye drops in presbyopic with sample 30 patienat Due to the effect of the medication on the near vision. Timepoint: Day one, Day 15, Day 30, Day 60, Day 90. Method of measurement: Measurement of refractive error of the eye in close and distant vision.;Amplitude of accommodation. Timepoint: Day one, Day 15, Day 30, Day 60, Day 90. Method of measurement: Based on the NPA method and lens.;Evaluation of side effects Like asthenopia, conjunctival hyperemia, blurred vision. Timepoint: Day one, Day 15, Day 30, Day 60, Day 90. Method of measurement: Based on Clinical Examination with Slit Lamp and Clinical history.

Secondary Outcome Measures

Name	Time	Method
The presence or absence of side effects of the medication on the patient's eyes. Timepoint: The first day after 2 weeks - again after 2 weeks - the next month - the next month. Method of measurement: By complete ophthalmic examinations with a slide machine by an ophthalmologist from the patient.