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Serum Carotenoids and Risk of Gastrointestinal Tract Cancer: Meta-analysis of Ten Studies

Completed
Conditions
Gastrointestinal Tract Cancer
Interventions
Other: serum carotenoids
Registration Number
NCT03433092
Lead Sponsor
Yong Zhou
Brief Summary

Previous studies have suggested that serum carotenoids may be associated with risk of gastrointestinal tract cancer (GIT cancer), but the results were inconsistent. Thus, the investigators conducted a meta-analysis to evaluate the associations between serum carotenoids and risk of GIT cancer.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
40641
Inclusion Criteria
  • The study had both case and control groups
  • Serum carotenoids levels, relative risk (RR) or OR and corresponding 95% CI were reported
  • Patients in case group were diagnosed with GIT cancer
Exclusion Criteria

·Animal studies

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Max Leenders et. al,2014serum carotenoids-
G Pappalardo et. al,1997serum carotenoids-
Yusuke Okuyama et. al,2014serum carotenoids-
GC Kabat et. al,2012serum carotenoids-
M Jenab et. al,2006serum carotenoids-
Christina Persson et. al,2008serum carotenoids-
Kenji Wakai et. al,2005serum carotenoids-
Jing Huang et. al, 2017serum carotenoids-
Christian C. Abnet et. al,2003serum carotenoids-
N Malila et. al,2002serum carotenoids-
Primary Outcome Measures
NameTimeMethod
Gastrointestinal Tract Cancer Incident MeasureThrough study completion, an average of 5 years.

The gastrointestinal tract cancer incident would be recorded during the follow-up years.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

West China Hospital, Sichuan University

🇨🇳

Chengdu, Sichuan, China

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