Effects Of Autologus Platelet- Rich Plasma on Pregnancy Rate in Intra Cytoplasmic Sperm Injection (ICSI) cycles in Repeated Implantation Failure Patients.

Not Applicable

Recruiting

• Conditions: INFERTILITY- recurrent implantation failure.; Complication associated with artificial fertilization, unspecified

• Registration Number: IRCT2017061034422N1
• Lead Sponsor: Avicenna Research Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

Inclusion Criteria: Patients who have had at least two unsuccessful embryo transfer cycles (fresh or frozen embryo); At least 6 good quality embryos (grade A or B) were transferred in previous cycles; Semen count=10 millions, normal morphology =3% in their husbands' semen analysis
Exclusion criteria: Patients with immunologic disorders (abnormality in CD markers, Anti TG, Anti TPO, ds DNA, ANA); Hematologic disorder; Genetic diseases; Uterus disorders; Hb<11 mg/dl and Platelet<150000/mm3; Systemic usage of corticosteroids during 14 days before use of PRP

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Chemical Pregnancy Rate. Timepoint: Two weeks after embryo transfer. Method of measurement: Blood Beta HCG.;Clinical Pregnancy Rate. Timepoint: Six weeks after embryo transfer. Method of measurement: Sonography. If normal fetal heart rate will be seen in sonography.

Secondary Outcome Measures

Name	Time	Method
Implantation Rate. Timepoint: Six weeks after embryo transfer. Method of measurement: Statistical method by (number of embryos transfer /number of pregnancy sacs in sonography 6 weeks after ET).