Comparison of the effect of inhaled salbutamol- ipratropium solution with and without inhaled furosemide solution on signs and symptoms, pulmonary function tests and inflammatory biomarkers in patients with exacerbation of chronic obstructive pulmonary disease.
Phase 2
Completed
- Conditions
- Chronic Obstructive Pulmonary Disease Exacerbations.Chronic obstructive pulmonary disease with (acute) exacerbationJ44.1
- Registration Number
- IRCT20240118060726N1
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 92
Inclusion Criteria
Definite diagnosis of exacerbation COPD disease
Age range of 20-65 years
Stable vital signs
Controlled and constant medication regimen during the study
Exclusion Criteria
Moderate to severe heart failure
Digestive problems such as severe nausea and vomiting
Cancers of the respiratory tract
Chronic kidney or liver disease
Surgery of the respiratory system over the past year
Pregnancy and breastfeeding
Allergy to sulfated drugs
Withdrawal from participating
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method