Clinical and Radiographic Evaluation of Platelets Rich Fibrin in Adult Pulpotomy: Randomized Clinical Trial

Al-Azhar University1 site in 1 country20 target enrollmentMarch 12, 2023

ConditionsIrreversible Pulpitis

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Irreversible Pulpitis
Sponsor: Al-Azhar University
Enrollment: 20
Locations: 1
Primary Endpoint: Radiographic changes in periapical area using periapical radiographs.
Status: Completed
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The goal of this interventional randomized clinical trial is to evaluate the use of platelet rich fibrin in full pulpotomy in mature adult teeth.

The main questions it aims to answer are:

Does the use of platelet rich fibrin in complete pulpotomy in mature permanent teeth will raise the success rate of full pulpotomy of adult teeth?
Does the use of cone beam computed tomography scans will be more effective in early detection of apical periodontitis than periapical radiographs?

Participants will be asked to do the following:

Receive the pulpotomy treatment of their target tooth.
Record the pain score in the pain assessment chart.
Attend the follow-up visits. They'll receive a full pulpotomy treatment of their target tooth. Researchers will evaluate the usage of platelet rich fibrin in performing the pulpotomy procedure of adult teeth and if cone beam computed tomography scans will be more effective in early detection of apical periodontitis than periapical radiographs.

Registry

clinicaltrials.gov

Start Date

March 12, 2023

End Date

March 23, 2024

Last Updated

last year

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Al-Azhar University

Responsible Party

Principal Investigator

Ahmed Ibrahim Ahmed Qandeel

Demonstrator of Endodontics, Faculty of Dental Medicine

Al-Azhar University

Eligibility Criteria

Inclusion Criteria

•Patient age: 25-35 years
•Mature permanent premolar teeth with two separate roots.
•Clinical diagnosis of irreversible pulpitis.
•Patients without existing medical condition.
•Exclusion criteria:
•Immature teeth.
•Non-restorable teeth.
•Non-vital Teeth.
•Uncontrolled pulpal bleeding.
•Periodontally affected teeth.

Exclusion Criteria

Not provided

Outcomes

Primary Outcomes

Radiographic changes in periapical area using periapical radiographs.

Time Frame: 6 and 12 months.

The radiographic changes was evaluated using periapical radiographs. the outcome was measured using the periapical index scoring 1,2,3,4 or 5 with 1 indicating normal and 5 indicates severe periodontitis with exacerbating features.