Clinical and Radiographic Evaluation of Platelets Rich Fibrin in Adult Pulpotomy: Randomized Clinical Trial
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Al-Azhar University
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Radiographic changes in periapical area using periapical radiographs.
Study Overview
Brief Summary
The goal of this interventional randomized clinical trial is to evaluate the use of platelet rich fibrin in full pulpotomy in mature adult teeth.
The main questions it aims to answer are:
- Does the use of platelet rich fibrin in complete pulpotomy in mature permanent teeth will raise the success rate of full pulpotomy of adult teeth?
- Does the use of cone beam computed tomography scans will be more effective in early detection of apical periodontitis than periapical radiographs?
Participants will be asked to do the following:
- Receive the pulpotomy treatment of their target tooth.
- Record the pain score in the pain assessment chart.
- Attend the follow-up visits. They'll receive a full pulpotomy treatment of their target tooth. Researchers will evaluate the usage of platelet rich fibrin in performing the pulpotomy procedure of adult teeth and if cone beam computed tomography scans will be more effective in early detection of apical periodontitis than periapical radiographs.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 25 Years to 35 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Patient age: 25-35 years
- •Mature permanent premolar teeth with two separate roots.
- •Clinical diagnosis of irreversible pulpitis.
- •Patients without existing medical condition.
Exclusion Criteria
- •Immature teeth.
- •Non-restorable teeth.
- •Non-vital Teeth.
- •Uncontrolled pulpal bleeding.
- •Periodontally affected teeth.
Arms & Interventions
Hydraulic Calcium Silicate Cement
Pulpotomy of adult teeth using Hydraulic Calcium Silicate Cement.
Intervention: Pulpotomy (Procedure)
platelet rich fibrin (PRF)
Pulpotomy of adult teeth using platelet Rich fibrin.
Intervention: Pulpotomy (Procedure)
Outcomes
Primary Outcomes
Radiographic changes in periapical area using periapical radiographs.
Time Frame: 6 and 12 months.
The radiographic changes was evaluated using periapical radiographs. the outcome was measured using the periapical index scoring 1,2,3,4 or 5 with 1 indicating normal and 5 indicates severe periodontitis with exacerbating features.
Secondary Outcomes
- Postoperative pain(Immediately, 24, 48, 72 hours and 7 days.)
Investigators
Ahmed Ibrahim Ahmed Qandeel
Demonstrator of Endodontics, Faculty of Dental Medicine
Al-Azhar University