NCT06729762招募中不适用
Ultrasound-guided Thermal Ablation for the Treatment of Benign Thyroid Nodules: A Multicenter Study
Chinese PLA General Hospital1 个研究点 分布在 1 个国家目标入组 1,500 人开始时间: 2024年12月9日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 1,500
- 试验地点
- 1
- 主要终点
- volume reduction rate
研究概览
简要总结
To evaluate long-term outcomes of ultrasound-guided thermal ablation for benign thyroid nodules
详细描述
To evaluate and predict long-term clinical outcomes of ultrasound-guided thermal ablation for benign thyroid nodules by a multicenter study
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •confirmation of benign nodule status on two separate fine- needle aspiration or core-needle biopsy
- •no suspicious malignant features on ultrasound examination
- •report of cosmetic and/ or symptomatic problems or concern of nodules growing rapidly or malignant transformation
- •refusal or ineligibility for surgery
- •follow-up time ≥12 months
排除标准
- •follicular neoplasm or malignancy findings on biopsy
- •nodules with benign result on biopsy had suspicious of malignancy in US
- •patients with contra-lateral vocal cord paralysis
- •previous radiation to the head and neck
- •follow- up time less than 12 months
结局指标
主要结局
volume reduction rate
时间窗: through study completion, an average of 6 months
The volume reduction rate (VRR)was calculated by the equations: VRR=(\[initial volume-final volume\] × 100)/initial volume
次要结局
- rate of complications(1 week)
- cosmetic score(through study completion, an average of 6 months)
- symptom score(through study completion, an average of 6 months)
- rate of nodule regrowth(through study completion, an average of 6 months)
- rate of change of thyroid function(through study completion, an average of 6 months)
- rate of disappearance(through study completion, an average of 6 months)
研究者
Yu-kun Luo
Clinical Professor
Chinese PLA General Hospital
研究点 (1)
Loading locations...
相似试验
招募中
不适用
Ultrasound-guided Thermal Ablation for Recurrent Thyroid CancerRecurrent Thyroid CancerNCT06733766Chinese PLA General Hospital300
招募中
不适用
Ultrasound-guided Thermal Ablation for Papillary Thyroid CarcinomaPapillary Thyroid CancerNCT06733740Chinese PLA General Hospital3,000
招募中
不适用
Ultrasound-guided Thermal Ablation for Bethesda III/IV Thyroid NodulesThyroid NoduleNCT06733753Chinese PLA General Hospital600
已完成
不适用
Effect of Ultrasound Guided Laser Ablation Therapy on Symptomatic Benign Thyroid NodulesThyroid NoduleNCT04277455Johnson Thomas10
进行中（未招募）
不适用
Cryoablation of Benign Thyroid Nodules: a Pilot StudyBenign Thyroid NoduleNCT06014229University of Sao Paulo General Hospital10