Omega-3 Fatty Acid Supplementation in Acne Patients
试验速览
- 阶段
- 3 期
- 状态
- 终止
- 入组人数
- 31
- 试验地点
- 2
- 主要终点
- Acne Lesion Count
研究概览
简要总结
60 patients receiving isotretinoin will be recruited from the UCLA acne specialty clinic. Subjects will be randomized in a 1:1 ratio to receive placebo or omega-3 1200mg twice a day for 24 weeks.
详细描述
Experimental Design
60 patients receiving isotretinoin will be recruited from the UCLA acne specialty clinic. Subjects will be randomized in a 1:1 ratio to receive placebo or omega-3 1200mg twice a day for 24 weeks.
Inclusion Criteria:
- Male or female above 18 years of age.
- Moderate to severe disease at the baseline of the study identified by their dermatologist.
- Will start treatment with systemic therapy for acne in the form of either isotretinoin or oral antibiotics.
- Patients able and willing to comply with the procedures in the study protocol.
Exclusion Criteria:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male or female above 18 years of age.
- •Moderate to severe disease at the baseline of the study identified by their dermatologist.
- •Will start treatment with systemic therapy for acne in the form of either isotretinoin or oral antibiotics.
- •Patients able and willing to comply with the procedures in the study protocol.
排除标准
- •Patients with history of taking omega-3 supplements for high triglyceride levels.
- •Patients taking medications for dyslipidemia, blood thinners, or high blood pressure medication.
- •Patients with a history of adverse reaction to omega-3 fatty acid supplementation.
- •Unwilling to give inform consent
研究组 & 干预措施
O3FA
Omega 3 Fatty Acid 1200mg twice a day for 24 weeks
干预措施: Placebo (Dietary Supplement)
Placebo
4 tablets twice a day for 24 weeks
干预措施: Placebo (Dietary Supplement)
O3FA
Omega 3 Fatty Acid 1200mg twice a day for 24 weeks
干预措施: Omega-3 (Dietary Supplement)
Placebo
4 tablets twice a day for 24 weeks
干预措施: Omega-3 (Dietary Supplement)
结局指标
主要结局
Acne Lesion Count
时间窗: up to 24 weeks
In all study patients being treated for acne, lesion counts will be assessed and evaluated for any differences between patients on omega-3 fatty acid supplementation and not on supplementation.
次要结局
未报告次要终点
研究者
Christina Kim, MD
Physician
Kaiser Permanente