临床试验/NCT00665262

NCT00665262已完成4 期

The Effect of the Combined Use of Naloxone and Tramacet on Postoperative Analgesia in Elderly Patients Having Joint Replacement Surgery: a Prospective Feasibility Study

Lawson Health Research Institute1 个研究点分布在 1 个国家目标入组 10 人开始时间: 2007年12月17日最近更新: 2017年8月28日

适应症

干预措施

试验速览

阶段: 4 期
状态: 已完成
发起方: Lawson Health Research Institute
入组人数: 10
试验地点: 1
主要终点: opoid use post knee/hip arthroplasty

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Ten patients 70 years and older having elective total hip/knee replacement surgery will be recruited to receive a continuous IV infusion of naloxone and oral tramacet for analgesia. Postoperative analgesia, satisfaction, side effects, need for rescure analgesia, and length of stay.

研究设计

研究类型: Interventional
分配方式: Na
干预模型: Single Group
主要目的: Treatment
盲法: None

入排标准

年龄范围: 70 Years 至 —（Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•aged 70 years or older able to give consent able to communicate in English having elective hip/knee arthroplasty ASA physical status 1-3

排除标准

•allergies to any of the following: naloxone, tramacet, NSAIDs, sulpha, or local anesthesic contraindication to spinal anesthesia contraindication to use of tramacet or celebrex ASA physical status4 chronic opiod use chronic pain syndrome

研究组 & 干预措施

1

Experimental

comibined use of tramacet and naloxone infusion perioperatively

干预措施: tramacet (Drug)

结局指标

主要结局

opoid use post knee/hip arthroplasty

时间窗: post-op period

次要结局

incidence of visual analogue scale scores greater than 4(post-op period)

研究者

发起方

Lawson Health Research Institute

申办方类型

Other

责任方

Sponsor

研究点 (1)

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