NCT06959446已完成不适用
Association Between Perioperative Homocysteine and Postoperative Complications/All-Cause Mortality in Elderly Patients Undergoing Non-Cardiac Surgery
Chinese PLA General Hospital0 个研究点目标入组 29,156 人开始时间: 2014年1月1日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 29,156
- 主要终点
- Acute kidney injury (AKI)
研究概览
简要总结
This study aims to explore the association between perioperative homocysteine (Hcy) levels and their pre-to-postoperative changes with postoperative complications and all-cause mortality in elderly patients undergoing non-cardiac surgery. Besides, the dynamic changes in Hcy levels may reflect metabolic shifts, highlighting their potential value in predicting adverse postoperative outcomes. These findings suggest that monitoring perioperative Hcy levels and their changes could help identify high-risk patients and inform postoperative management strategies.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 65 Years 至 —(Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Hospitalized older (≥ 65 years) patients underwent non-cardiac surgery
排除标准
- •Without preoperative Hcy data (n= 44115)
- •Neurosurgery (n= 3343)
- •Kidney or renal artery surgery (n= 2478)
- •Chronic kidney disease (n=577)
结局指标
主要结局
Acute kidney injury (AKI)
时间窗: January 2014 - August 2019
次要结局
- mortality(January 2014 - August 2020)
研究者
Jingsheng Lou
Professor
Chinese PLA General Hospital
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