Influence of remote ischemic preconditioning on cardiac function after endurance exercise

Completed

• Conditions: acute myocardial infarction; athlete's hart; 10028593

• Registration Number: NL-OMON39515
• Lead Sponsor: Medisch Universitair Ziekenhuis Maastricht

Brief Summary

Trial is onging in other countries

Detailed Description

Not available

Study Timeline

• Study Completion: 2013-06-30
• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 29

Inclusion Criteria

Informed consent
Healthy
Age between 18 and 65 years
Endurance-trained (two or more training sessions per week)

Exclusion Criteria

Not applicable

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Serum concentration of cardiac troponins (T and I) at baseline, pre-exercise<br /><br>and 0, 2, 4, 6, 8, 10 hours post-exercise. Indices of cardiac function measured<br /><br>at baseline and immediately post-exercise. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Other cardiac markers: e.g. NT-proBNP<br /><br>Various molecular forms of cardiac troponin T and I<br /><br>Markers to correct variation in renal function during exercise: e.g. creatinin,<br /><br>cystatin C, albumin, hematocrit.<br /><br>Inflammatory markers: e.g. CRP<br /><br>Oxidative status: e.g. thiobarbituric acid reactive substances (TBARS), trolox<br /><br>equivalent anti-oxidant capacity (TEAC), erythrocyte susceptibility to in vitro<br /><br>peroxidation.<br /><br>Heart rate<br /><br>Duration of 30km-run<br /><br>Baseline blood pressure</p><br>