NL-OMON35680已完成不适用
Anti TNF therapy and susceptibility for Coxiella burnetii infection - Anti TNF therapy and susceptibility for Coxiella burnetii infection
niversitair Medisch Centrum Sint Radboud0 个研究点目标入组 800 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 800
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Diagnosis of either rheumatoid arthritis (RA), arthritis psoriatica or bechterew disease
- •Residence in Q fever endemic area (defined by the Institute for Public Health and Environment (RIVM) as *core area*), as determined by the postal code of their home address.
- •Signed written informed consent ;For patients on anti-TNF therapy:
- •Treatment with TNFa blockers either infliximab, etanercept or adalimumab in an adequate dose according to the guidelines
- •Treatment with TNFa blockers is started before 01-01-2011 ;For patients not receiving anti-TNF therapy:
- •Treatment with DMARDs
- •No history of treatment with TNFa blockers
排除标准
- •Age under 18 years
- •Pregnancy or lactation
- •Lymphoma, lymphoproliferative syndromes and other hematologic malignancies
- •Chronic infections, including HIV, hepatitis B or C, mycobacterial disease
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