Skip to main content
Clinical Trials/NCT02371928
NCT02371928
Completed
Not Applicable

A Neuromuscular Exercise Program for Patients With Anterior Shoulder Instability: A Randomized Controlled Trial

University of Southern Denmark4 sites in 1 country56 target enrollmentFebruary 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Shoulder Dislocation
Sponsor
University of Southern Denmark
Enrollment
56
Locations
4
Primary Endpoint
Change in Western Ontario Shoulder Instability Index (WOSI)
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

This study is designed to investigate the efficacy and safety of a supervised neuromuscular exercise program versus a standard home exercise program for patients with post-traumatic symptomatic anterior shoulder instability.

Participants with at least one week of symptom duration are randomly assigned to either a 12-week structured, supervised Shoulder Instability Neuromuscular EXercise (SINEX) program versus a standard HOMe EXercise (HOMEX) program.

The H1-hypothesis is that the SINEX program results in a greater increase in quality of life and physical function than the HOMEX program at the primary endpoint at three months follow-up from baseline

Detailed Description

A common, and very painful, injury for individuals in their second and third decades is a traumatic dislocated shoulder. This injury accounts for almost 50% of all joint dislocations registered in the emergency departments. Due to post-traumatic laxity and injuries to the surrounding shoulder tissue, one major problem is the risk of developing a chronic recurrent instable shoulder affecting patients both physically and psychologically decreasing their overall quality of life. Biomechanically, proprioceptive changes and decreased sensorimotor control are found in patients with post-traumatic shoulder instability inhibiting the ability to control and stabilize the glenohumeral joint. In other similar musculoskeletal disorders, recent studies clearly shows positive effects of progressive neuromuscular exercise. Finally, no studies have yet investigated the effect of a structured, physical exercise-training regime based on neuromuscular principles targeting the shoulder joint. This trial is performed as a randomized, assessor-blinded, controlled multi-center trial with cooperation from various shoulder outpatient clinics located at different hospitals in The Region of Southern and Northern Denmark.

Registry
clinicaltrials.gov
Start Date
February 2015
End Date
June 2017
Last Updated
8 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Henrik Eshoj

Msc, PhD. stud

University of Southern Denmark

Eligibility Criteria

Inclusion Criteria

  • Age between 18-39
  • Minimum one radiographic verified anterior shoulder dislocation (total dissociation of the humeral head to the glenoid)
  • Limited ability to maintain a desired level of physical activity (sports/leisure/work) due to pain and/or symptoms in the affected shoulder within the latest week.

Exclusion Criteria

  • Humeral fracture and/or bony bankart (visible on conventional radiographs at the time of presentation) warranted for surgery decided by the orthopedic (no other axial or appendicular musculoskeletal injury)
  • Prior surgery in affected shoulder joint
  • \>5 anterior shoulder dislocations (verified by journal or subjective evaluation)
  • Suspected competing diagnosis (e.g. rheumatoid arthritis, cancer, neurological disorders, fibromyalgia, schizophrenia, suicidal threatened, borderline personality disorder or obsessive compulsive disorder
  • Sensory and motor deficits in neck and shoulder
  • Inadequacy in written and spoken Danish
  • Not willing or able to attend 12 weeks of supervised exercise therapy

Outcomes

Primary Outcomes

Change in Western Ontario Shoulder Instability Index (WOSI)

Time Frame: Primary: 3 months. Other: 12, 24 months

The patient reported outcome, WOSI, consists of four domains covering "Physical Symptoms", "Sport/Recreation/Work", "Lifestyle" and "Emotions" with 21-item questionnaires in all. Each item is scored using a horizontal visual scale ranging from 0 to 100 mm (0-2100, with 0 as the level of no trouble).

Secondary Outcomes

  • Change in Euro Qol 5D Index (EQ-5D)(3,12, 24 months)
  • Change in Tampa Scale of Kinesiophobia(3,12, 24 months)
  • Change in the four sub-scales (domains) of WOSI(3,12, 24 months)
  • Change in Patient Specific Functioning Scale(3 months)
  • Global Perceived Effect(3 months)
  • Change in Constant-Murley Shoulder Score(3 months)
  • Number of changes in positive clinical tests for anterior shoulder instability(3 months)
  • Change in shoulder joint position sense(3 months)
  • Number of participants with adverse events(3 months)

Study Sites (4)

Loading locations...

Similar Trials