REcurrent LArynx tumor or Treatment Effects?

Recruiting

• Conditions: laryngeal cancer; Recurrent laryngeal and hypopharyngeal carcinoma; 10027655

• Registration Number: NL-OMON55291
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

- Recurrent laryngeal or hypopharyngeal carcinoma after primary radiotherapy
- Scheduled for salvage total laryngectomy
- >=18 years of age
- Given informed consent

Exclusion Criteria

- Patients who meet exclusion criteria for MRI at 3T as defined in the
protocols of the radiology department
- Patients with contraindication for CT contrast administration as defined in
the protocols of the radiology department

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The accuracy of DCE- and DWI-MRI based parameters based parameters in the<br /><br>differentiation of recurrent tumor tissue and radiation induced changes</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Improvement of radiologists* delineation of tumor recurrences on imaging when<br /><br>given the results of this study.<br /><br>The accuracy of FDG-PET and CT based parameters in the differentiation of<br /><br>recurrent tumor tissue and radiation induced changes.</p><br>