NCT04113356招募中不适用
Clinical Relevance of Magnetic Resonance Imaging in Acute ST-Elevation Myocardial Infarction
Medical University Innsbruck2 个研究点 分布在 1 个国家目标入组 1,500 人开始时间: 2011年1月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 1,500
- 试验地点
- 2
- 主要终点
- Occurence of major adverse cardiovascular events
研究概览
简要总结
Cardiovascular magnetic resonance imaging enables comprehensive assessment of cardiovascular function, morphology and pathology. The investigators aim to evaluate the nature and clinical significance of magnetic resonance imaging parameters in patients presenting with first acute ST-elevation myocardial infarction.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Occurence of major adverse cardiovascular events
时间窗: 1 - 5 years
次要结局
- Aortic pulse wave velocity and distensibility by phase contrast imaging(baseline, 4 months and 12 months)
- Cardiac function by cine imaging(baseline, 4 months and 12 months)
- Parameters of cardiac function by transthoracic echocardiography(baseline, 4 months and 12 months)
- Cardiac autonomic function(baseline, 4 months and 12 months)
- Infarct size assessment (% of left ventricular myocardial mass)(baseline, 4 months and 12 months)
- Assessment of infarct transmurality grade (%) with late gadolinium enhancement imaging(baseline, 4 months and 12 months)
- Occurence and area of microvascular obstruction(baseline)
- Intramyocardial haemorrhage assessed by T2* imaging(baseline, 4 months and 12 months)
- Tissue characterisation by T1, T2 and T2* Mapping(baseline, 4 months and 12 months)
- Myocardial deformation by strain analysis(baseline, 4 months and 12 months)
- Aortic pulse wave distensibility by phase contrast imaging(baseline, 4 months and 12 months)
- Quality of life and invalidity assessment (Global Physical Activity Questionnaire)(1 - 5 years)
- Biomarker release during the acute and subacute phase(baseline, 4 months and 12 months)
- Plaque volume by 3D ultrasound(baseline, 12 months)
- Chamber volumes by cine imaging(baseline, 4 months and 12 months)
- Stroke volumes by phase contrast imaging(baseline, 4 months and 12 months)
研究者
研究点 (2)
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