ACTRN12609000593235进行中（未招募）4 期
Efficacy of Zoledronate in fracture prevention in osteopenic postmenopausal women.
Professor Ian Reid0 个研究点目标入组 2,000 人开始时间: 2009年7月17日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 2,000
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 65 Years 至 85 Years（—）
- 性别
- Female
入选标准
- •Female subjects only will be studied
- •They must be >5years postmenopausal and aged >65 years
- •Life expectancy >5years
- •Total hip T-score <-1.0 and >-2.5 at either hip
排除标准
- •Renal impairment (estimated Glomerular Filtration Rate <30 ml/minute)
- •Untreated hypo or hyperthyroidism
- •Active liver disease
- •Concurrent major systemic disease
- •Active malignancey (other than skin cancers) within the last 2 years or still requiring treatment (eg anti-estrogens)
- •Metabolic bone disease
- •Regular use of Hormone Replacement Therapy within the previous 1 year
- •Treatment with bisphosphonates in the previous 1 year
- •Current treatment with glucocorticoid drugs
- •Regular use of other bone-active drugs in the previous year
- •Bone Mineral Density of Lumbar spine (L1-4) <-3.0
研究者
相似试验
进行中（未招募）
1 期
Zoledronate against fractures in children with cerebral palsycerebral palsy, osteopenia, fractureMedDRA version: 20.0Level: PTClassification code 10049088Term: OsteopeniaSystem Organ Class: 10028395 - Musculoskeletal and connective tissue disordersMedDRA version: 15.1Level: HLTClassification code 10034157Term: Pathological fractures and complicationsSystem Organ Class: 100000005035MedDRA version: 20.0Level: PTClassification code 10049904Term: Osteoporosis prophylaxisSystem Organ Class: 10042613 - Surgical and medical proceduresMedDRA version: 20.0Level: LLTClassification code 10021740Term: Infantile cerebral palsySystem Organ Class: 100000012650MedDRA version: 20.0Level: PTClassification code 10006002Term: Bone painSystem Organ Class: 10028395 - Musculoskeletal and connective tissue disordersMedDRA version: 20.0Level: LLTClassification code 10013522Term: Disuse osteoporosisSystem Organ Class: 100000018618EUCTR2014-002118-21-DKRanders Regional Hospital
进行中（未招募）
1 期
Zoledronate Early to Hip Fractures Patients – safe and effective? A Randomized controlled double-blinded treatment strategy trial on Zoledronate in hip fracture patients: The ZEBRA trialHip fractureCTIS2023-510198-32-00Oslo University Hospital HF300
已完成
3 期
Zoledronate in Preventing Skeletal (Bone)-Related Events in Men Who Are Receiving Androgen Deprivation Therapy For Prostate Cancer and Bone MetastasesMetastatic CancerProstate CancerNCT00079001Alliance for Clinical Trials in Oncology645
已完成
不适用
Effect of Zolendronate in patients of celiac diseaseCTRI/2015/06/005863Dr Sanjay Kumar Bhadada50
已完成
4 期
Zoledronate Early to Hip Fracture Patients - Safe and Effective?Hip FracturesOsteoporosisNCT05025293Lene Bergendal Solberg228