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The Motor Imagery Based on Action Observation Treatment on Dysphagia in Wallenberg Syndrome

Not Applicable
Completed
Conditions
Deglutition Disorders
Lateral Medullary Syndrome
Interventions
Other: conventional dysphagia treatment
Other: motor imagery based on action observation treatment
Registration Number
NCT06224686
Lead Sponsor
Le Wang
Brief Summary

The goal of this clinical trial is to learn about on dysphagia in wallenberg syndrome. The main questions it aims to answer are:

* the efficacy of motor imagery based on action observation treatment in the rehabilitation of patients with dysphagia in Wallenberg syndrome.

* apply functional near infrared spectroscopy to explore the mechanism of action of this therapy.

Participants received conventional dysphagia treatment and motor imagery based on action observation treatment once a day for 14 days. Researchers compared the control group to see the effect and mechanism of motor imagery based on action observation treatment.

Detailed Description

The goal of this clinical trial is to learn about on dysphagia in wallenberg syndrome. The main questions it aims to answer are:

* the efficacy of motor imagery based on action observation treatment in the rehabilitation of patients with dysphagia in Wallenberg syndrome.

* apply functional near infrared spectroscopy to explore the mechanism of action of this therapy.

Both groups received conventional dysphagia treatment, and the experimental group underwent the addition of motor imagery based on action observation treatment to the control group once a day for 14 days. Overall swallowing function was assessed before treatment and after 14 days of intervention. Meanwhile, the functional near infrared spectroscopy was used to detect changes in cerebral hemodynamics during the execution of volitional swallowing task and swallowing motor imagery.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
30
Inclusion Criteria
  • age ranged from 18-80 years and right-handed;
  • first onset, vital signs stable and conscious;
  • the dysphagia confirmed by videofluoroscopic swallowing study;
  • no cognitive impairment, the mini-mental state examination score: >17 for those with an illiterate education, >20 for those with an elementary education, and >24 for those with a secondary education and above;
  • good motor imagery ability with kinesthetic and visual imagery questionnaire-10 score ≥25;
  • cranial integrity without craniotomy and/or craniectomy;
  • patient and/or his/her relative agrees and signs written informed consent.
Exclusion Criteria
  • combined ischemic foci at other sites;
  • presence of organic swallowing dysfunction or pre-existing dysphagia due to Parkinson's disease, dementia, and others;
  • severe cardiac, pulmonary, hepatic, and renal insufficiency and vital organ failure;
  • significant psychological disorders such as anxiety and depression;
  • infected or broken skin on the head;
  • poorly controlled epilepsy;
  • poor patient compliance.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
The experimental groupconventional dysphagia treatmentconventional dysphagia treatment and motor imagery based on action observation treatment
The experimental groupmotor imagery based on action observation treatmentconventional dysphagia treatment and motor imagery based on action observation treatment
The control groupconventional dysphagia treatmentconventional dysphagia treatment
Primary Outcome Measures
NameTimeMethod
standardized swallowing assessmentday 1 and day 14

The standardized swallowing assessment was used to assess the improvement of overall swallowing function, it has a maximum score of 46 and a minimum score of 18, with lower scores indicating better swallowing function.

cortical activation during swallowing motor imageryday 1

The functional near infrared spectroscopy system (Nirsmart, Danyang Huichuang Medical Equipment Co., Ltd., China) was used to detect changes in cerebralhemodynamics during the whole swallowing motor imagery.

cortical activation during volitional swallowingday 1 and day 14

The functional near infrared spectroscopy system (Nirsmart, Danyang Huichuang Medical Equipment Co., Ltd., China) was used to detect changes in cerebralhemodynamics during the execution of volitional swallowing task.

Secondary Outcome Measures
NameTimeMethod
swallowing-quality of lifeday 1 and day 14

Swallowing-quality of life has a score range of 44 - 220, with lower scores indicating poorer swallowing function and poorer quality of life.

yale pharyngeal residue severity rating scaleday 1 and day 14

Yale pharyngeal residue severity rating scale scores were measured using a 5-point ordinal scale: Ⅰ = none, Ⅱ = trace, Ⅲ = mild, Ⅳ = moderate, Ⅴ = severe.

Rosenbek penetration-aspiration scaleday 1 and day 14

The highest PAS score is 8 and the lowest is 1 (1 = no entry of material into the airway; 2 - 5 = penetration of material past the laryngeal additus into the supraglottic space and traveling as far as the true vocal folds; 6 - 8 = tracheal aspiration of material below the true vocal folds).

Murray secretion scaleday 1 and day 14

The severity of Murray secretion scale was measured using a grade of 0-3, patients without obvious saliva accumulation are scored as MSS grade 0, whereas patients who had secretions in the laryngeal vestibule at the start of the exam were assigned grade 3.

Trial Locations

Locations (1)

The First Affiliated Hospital of Zhengzhou University

🇨🇳

Zhengzhou, Henan, China

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