Use of Acellular Dermal in the Incarcerated Inguinal Hernia Tension-free Reconstructions
- Conditions
- Incarcerated Inguinal Hernia
- Interventions
- Procedure: ADM tension-free hernia reparation
- Registration Number
- NCT02469142
- Lead Sponsor
- Xijing Hospital of Digestive Diseases
- Brief Summary
Incarcerated inguinal hernia is one of the common acute abdomen abdominal surgery, often prone to intestinal necrosis and acute peritonitis.Using traditional tension hernia reparation, the recurrence rate were as high as 30%. In recent years, biological materials especially acellular matrix materials (Acellular Dermal Matrix, ADM) in resisting the infection, has become a research hotspot. In the project, the investigators try to address the role of ADM in incarcerated inguinal hernia patients.
- Detailed Description
observation indicator:
1. recurrence rate after operation
2. incidence rate of complications
3. postoperative hospital stay
4. hospitalization costs
5. Self-evaluation of gastroesophageal reflux symptoms and quality of life(QOL) in 6th-month, 1st-year,2nd-year,3rd-year,4th-year and 5th-year after operation
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 100
- Clinical diagnosis of incarcerated hernia
- randomly select patch agreed by patients and family members
- severe organ dysfunction
- No-tolerate anesthesia
- No-suitable for operation
- glucocorticoid with long-term use
- Sever intraperitoneal adhesion existed
- spirit disease patients
- automatically exit
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description ADM tension-free hernia reparation ADM tension-free hernia reparation Use ADM to repair incarcerated inguinal hernia by tension-free
- Primary Outcome Measures
Name Time Method the recurrence rate after operation ten years
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Xijing Hospital
🇨🇳Xi'an, Shanxi, China