Video autofluorescence imaging for detection of adenomatous POLyps of the colon in intermediate and high-risk PAtieNts
Completed
- Conditions
- Cancer, polypsCancerColorectal cancer
- Registration Number
- ISRCTN76121851
- Lead Sponsor
- Academic Medical Centre (AMC) (The Netherlands)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
1. Previous adenomatous polyp (polyp-surveillance)
2. Previous adenocarcinoma of the colon for which a partial colectomy was performed
3. Hereditary non-polyposis colorectal cancer (either genetically proven by a mutation in one of the mismatch repair genes or with a clinical diagnosis according to the Amsterdam II criteria)
4. Positive family history for colorectal cancer (CRC): a first-degree family-member fulfills one of the revised Bethesda criteria
Exclusion Criteria
1. Familiar adenomatous polyposis
2. History of inflammatory bowel disease
3. Severe coagulopathy
4. Age less than 18 years
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The sensitivity of high resolution white light endoscopy will be compared to that of AFI for detection of polyps and cancer in the colon.
- Secondary Outcome Measures
Name Time Method o secondary outcome measures