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临床试验/CTRI/2018/02/012124
CTRI/2018/02/012124已完成4 期

Peri-operative risk factors for pulmonary complications after non-cardiac surgery

Radhika Dhanpal and Surbhi Gupta1 个研究点 分布在 1 个国家目标入组 1,170 人开始时间: 2016年1月3日最近更新:
适应症

试验速览

阶段
4 期
状态
已完成
发起方
入组人数
1,170
试验地点
1
主要终点
To determine peri-operative risk factors for pulmonary complications after non-cardiac surgery

研究概览

简要总结

59out of 1170 patients developed postoperative pulmonary complications (PPCs).

Univariateanalysis showed that the presence of anemia (hemoglobin < 10 gm%) , positive cough test, type of surgery as emergency surgery, type ofanesthesia as general anaesthesia , increased duration of surgery (> 2 hours),  presence of preoperative nasogastric tube,intraoperative blood transfusion, higher patient age (>50 years), presenceof preoperative respiratory symptoms (cough, sputum, dyspnea)  and increased ARISCAT score weresignificantly associated with the presence of postoperative pulmonarycomplications.

Multivariateanalysis revealed that higher ARISCAT score and patients with higher age hadhigher odds of developing PPC. Patients who had positive cough test andpresence of preoperative  nasogastrictube were other independent risk factors associated with the presence of PPC.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • •under general anaesthesia
  • •under regional anaersthesia
  • •under neuraxial block
  • •non-cardiac surgey.

排除标准

  • •age less than 18 years
  • •obsteteric procedures
  • •procedures related to a previous post-operative complications 4.transplantation procedures 5.patient with pre-intubated trachea
  • •out patient procedure (hosptital stay less than 24 hrs)
  • •morbidly obese.

结局指标

主要结局

To determine peri-operative risk factors for pulmonary complications after non-cardiac surgery

时间窗: Patients were followed up every day till the day they were discharged from the hospital

次要结局

  • Patients who were re-explored had higher incidence of post-operative complications(1 month)

研究者

发起方
Radhika Dhanpal and Surbhi Gupta
申办方类型
Other [self]

研究点 (1)

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