Metabolic and Infectious Diseases in La Réunion (the REUNION Population-based Study)

• Conditions: General Population; Metabolic Disease; Infectious Disease; Cardiovascular Diseases
• Interventions: Diagnostic Test: Blood, DNA, feces, urine, hair and skin microbiota collection

• Registration Number: NCT05400824
• Lead Sponsor: Institut National de la Santé Et de la Recherche Médicale, France

Brief Summary

The aim of the present study is to determine the prevalence of cardiometabolic and infectious disease in La Reunion (french oversea department and region of France).

Known or suspected risk factor for these diseases will also be assessed, such as microbiota, cognitive impairement, social inequalities, and genetics.

Detailed Description

Overall, 2000 men and women will be recruited during two years for an extensive clinical examination including a microbiota, blood, hair and DNA collection, cognitive tests, autonomous nervous system assessment, spirometry, pulse wave velocity measurement, a carotid doppler echo tracking.

Study Timeline

• Status Verified: 2022-05
• Study Start: 2022-05-01
• Study First Submitted: 2022-05-27
• Study First Submitted QC: 2022-05-27
• Study First Posted: 2022-06-02
• Last Update Submitted: 2022-06-29
• Last Update Posted: 2022-07-05
• Primary Completion: 2024-05
• Study Completion: 2024-05

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 2000

Inclusion Criteria

• 18-67 years
• given consent for genetic analysis,
• written consent for participating in the study

Exclusion Criteria

• judicial protection or guardianship

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
general population	Blood, DNA, feces, urine, hair and skin microbiota collection	Observational study of 2000 adult men and women from the general population who will benefit from a free extensive health check up in La Reunion

Primary Outcome Measures

Name	Time	Method
Prevalence of cardiometabolic diseases	cross sectional (at inclusion)	Prevalence rates for diabetes, hypertension, obesity, dyslipidemia, smoking and subclinical atherosclerosis markers
Prevalence of infectious diseases	cross sectional (at inclusion)	Seroprevalence rates for chikungunya, dengue, zika, covid19

Trial Locations

Locations (1)

Centre Hospitalier Universitaire de La Réunion; 🇫🇷 La Réunion, Saint-Pierre, France