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Clinical Trials/NCT05325671
NCT05325671
Completed
N/A

Efficacy of Postoperative Pain Control Between Transarticular VS Periartiucular Multimodal Drug Infiltration in Total Hip Arthroplasty: Double-blinded Randomized Control Trial

Rajavithi Hospital1 site in 1 country120 target enrollmentApril 5, 2022

Overview

Phase
N/A
Intervention
Not specified
Conditions
Pain, Post Operative
Sponsor
Rajavithi Hospital
Enrollment
120
Locations
1
Primary Endpoint
Visual analogue scale at rest on postoperative day1st and 2nd
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

This research aim to improve postoperative outcome in total hip arthroplasty(THA) by using local mixture infiltration as bupivacaine + NSAID + epinephrine + tranxemic acid. In the present time these mixture components has shown to improve THA outcome by aspect of postoperative pain control, postoperative opioid consumption, postoperative bleeding, LOS and postoperative rehabilitation without increasing complication but the accuracy of infiltration technique which gives the best outcome has not been yet discovered.Recently study by Hashimoto et al has risen that these technique can be administrated by both periarticular and intra-articular approach.By considering the complexity of human anatomy around the hip tissue we assume that the intra-articular(transarticular) may given equivalence (may be better) outcome with lowering procedural related complication comparing to periarticular infiltration approach.

Registry
clinicaltrials.gov
Start Date
April 5, 2022
End Date
October 31, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • patient who would go on cemented and cementless THA
  • age 45-60 years of age
  • voluntary decision exclusion criteria
  • bilateral THA
  • revision surgery
  • history of pelvic and hip surgery previously
  • allergy to medication in protocol
  • CKD stage 4-5, chronic liver disease with Child Pugh B or C
  • pregnancy
  • history of hip injection

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Visual analogue scale at rest on postoperative day1st and 2nd

Time Frame: 1 week

Secondary Outcomes

  • total morphine consumption in whole postoperative period(1 week)
  • total morphine consumption in first 24 hours postoperative period via PCA pump(1 week)
  • length of stay(1 week)
  • postoperative complication(1 week)

Study Sites (1)

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