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A Study to Access the Efficacy and Safety of Meloxicam in Patients With Osteoarthritis of the Knee

Phase 4
Completed
Conditions
Osteoarthritis
Interventions
Registration Number
NCT02183116
Lead Sponsor
Boehringer Ingelheim
Brief Summary

To Access the Efficacy and Safety of Meloxicam 7.5mg once daily over a treatment period of 56 days

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
30
Inclusion Criteria
  • Osteoarthritis of the knee requiring the therapy with non-steroidal anti-inflammatory drugs (NSAIDs)
Exclusion Criteria

none

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
MeloxicamMeloxicam-
Primary Outcome Measures
NameTimeMethod
Change from baseline in pain on active movement assessed by a 100 mm visual analogue scale (100 mm, VAS)Baseline, 8 weeks after first drug administration
Secondary Outcome Measures
NameTimeMethod
Change from baseline in Lequesne indexBaseline, 8 weeks after first drug administration
Change from baseline in physical examination (tenderness)Baseline, 8 weeks after first drug administration
Assessment of significant change from baseline in status according endoscopyBaseline, 8 weeks after first drug administration
Assessment of significant change from baseline in gastrointestinal (GI) symptoms scoreBaseline, 8 weeks after first drug administration
Assessment of significant change from baseline in laboratory valuesBaseline, 8 weeks after first drug administration
Number of Patients with Adverse EventsUp to 8 weeks after first drug administration
Assessment of significant change from baseline in physical examination (swelling)Baseline, 8 weeks after treatment
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