The Cervix as a Natural Tamponade in Postpartum Hemorrhage Caused by Placenta Previa and Placenta Previa Accreta: a Prospective Study
试验速览
- 阶段
- 不适用
- 发起方
- 试验地点
- 2
- 主要终点
- Successful control of postpartum haemorrhage (PPH)
研究概览
简要总结
Placenta previa and placenta accrete carry significant maternal and fetal morbidity and mortality. Several techniques have been described in the literature for controlling massive bleeding associated with placenta previa cesarean sections. The aim of this study is to evaluate the efficacy and safety of the use of the cervix as a natural tamponade in controlling postpartum hemorrhage caused by placenta previa and placenta previa accreta.
详细描述
Background: Placenta previa and placenta accrete carry significant maternal and fetal morbidity and mortality. The maternal mortality in women with placenta accreta may reach as high as 7-10%. Several techniques have been described in the literature for controlling massive bleeding associated with placenta previa cesarean sections, including uterine packing with gauze, balloon tamponades, the B-Lynch suture, insertion of parallel vertical compression sutures, a square suturing technique and embolization or ligation of the uterine and internal iliac arteries, but there is a wide variation in the success rate of these maneuvers. In a case report, Dawlatly et al. (2007) described a simple technique of suturing an inverted lip of the cervix over the bleeding placental bed that was successful in controlling the bleeding, saving the patient's life, and preserving her uterus.
The objective of this trial is to evaluate the safety and efficacy of the use of this Dawlatly stitch as a natural tamponade for controlling postpartum haemorrhage in cases of placenta previa and/ or placenta previa accreta.
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
入排标准
- 年龄范围
- 18 Years 至 40 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •All participating women had one or more previous cesarean deliveries.
- •were diagnosed with placenta previa and/ or placenta previa accreta by ultrasound. When the ultrasound result was not conclusive for placenta accreta, MRI was performed.
- •All participating women desired to preserve their fertility
- •Patients with focal (partial) placenta previa accreta/ placenta previa.
排除标准
- •placenta percreta.
- •diffuse placenta accreta or increta.
- •uncontrollable postpartum hemorrhage.
结局指标
主要结局
Successful control of postpartum haemorrhage (PPH)
时间窗: Intra-operative and up to 24 hours postpartum
Control of PPH and vaginal bleeding after employing the technique
Number of cases undergoing hysterectomy to control PPH
时间窗: Intra-operative and up to 24 hours postpartum
Failure of the technique to stop PPH and need for hysterectomy to stop the bleeding
Incidence of complications
时间窗: short term (intraoperative and up to 6 weeks postpartum)-long term:up to 2 years postpartum
次要结局
未报告次要终点
研究者
Ahmed Rabie Abdelraheim
Dr Ahmed Rabie Abdelraheim, lecturer of Obstetrics And Gynaecology
Minia University
