The effect of a selective serotonin reuptake inhibitor (SSRI) on the brain's response to light

Phase 4

Recruiting

• Conditions: Depressive disorders; Mental Health - Depression

• Registration Number: ACTRN12618000885291
• Lead Sponsor: Monash University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-05-25
• Last Update Posted: 16 September 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

Healthy Caucasian males and females

Exclusion Criteria

- Any current diagnoses of psychiatric illness or use of psychiatric medication
- Current sleep disorders or erratic/unusual sleep patterns
- Recent or excessive illicit drug use
- Current use of any prescription medication
- Colourblindness
- Recent surgery involving a full anaesthetic
- Any night shift work within the past 3 months
- Any travel outside of the current time zone within the last 3 months
- BMI less than 18 or greater than 30
- Use of hormonal contraception
- Abnormal menstrual cycle (abnormally long, short or unpredictable)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in suprachiasmatic area activation to light measured with fMRI[Assessed at each fMRI scan (2 total, with ~one week between scans)]

Secondary Outcome Measures

Name	Time	Method
Change in neural activation related to arousal measured with fMRI[Assessed at each fMRI scan (2 total, with ~one week between scans)]