Evaluation of the effects of Resveratrol Supplementation on Hepatic Enzymes, Inflammatory Factors, Lipid profile, blood glucose, Insulin Sensitivity, and Hepatic fibrosis in patients with Nonalcoholic Fatty Liver Disease.
Phase 2
- Conditions
- on Alcoholic Fatty Liver.Inflammatory liver disease, unspecified
- Registration Number
- IRCT201202014010N7
- Lead Sponsor
- ational Nutrition and Food Technology Research Institute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Age 18 and older; Evidence of nonalcoholic steatohepatitis with steatosis grade higher or equal to 1 in ultrasonography; No history of Alcohol consumption or consuming less than 10 grams alcohol per day in women and less than 20 grams per day in men; Absence of other liver disorders, malignancies, cardiovascular, respiratory, and kidney disorders; Absence of pregnancy or lactation; Absence of taking any medications in the past three months; Absence of weight loss in the recent three months; Absence of endocrine and metabolism disorders. Exclusion criteria: Weight loss more than 10% of baseline body weight during the intervention period. Pregnancy; Disliking to continue the study.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method iver Enzymes. Timepoint: at the first and at the 12th week of the study. Method of measurement: Biochemical analysis.
- Secondary Outcome Measures
Name Time Method iver fibrosis. Timepoint: at the first and the end of the study. Method of measurement: Fibroscan.