Comparison of intrathecal morphine with continuous patient-controlled epidural anesthesia versus intrathecal morphine alone for post-cesarean section analgesia: a randomized controlled trial
Not Applicable
- Conditions
- pregnancy
- Registration Number
- JPRN-UMIN000032475
- Lead Sponsor
- Asahikawa Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Female
- Target Recruitment
- 46
Inclusion Criteria
Not provided
Exclusion Criteria
We excluded patients with contraindications for spinal or epidural anesthesia due to hemodynamic, infectious, hemostatic, neurological statuses, and medication use. In addition, we excluded cases of which we were unable to obtain informed consent such as extremely emergent caesarean sections and cases of which general anesthesia was selected for reasons such as urgency or prediction of massive hemorrhage.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome of this study is postoperative pain as measured by NRS at 12 hours after intrathecal administration of morphine at rest and during mobilization
- Secondary Outcome Measures
Name Time Method Secondary outcomes are NRS and Bromage score at 4, 8, 24, 48 hours after intrathecal administration of morphine at rest and during mobilization, the number of patients who requested rescue analgesics, the number of requests for rescue analgesics per patient, the interval time before the first request of rescue analgesics, the incidence of delayed ambulation, and the incidence of requested treatment for pruritus and postoperative nausea and vomiting (PONV) during the first 24 hours after intrathecal administration of morphine.