The Effect of Serum Calcium Levels on Postoperative Pain: A Prospective Observational Study
- Conditions
- Postoperative Pain
- Registration Number
- NCT06957158
- Brief Summary
This is a prospective observational study. To investigate the effect of serum calcium levels on postoperative pain in patients undergoing abdominal surgery, and to determine whether changes in serum calcium levels are a risk factor for postoperative pain.
- Detailed Description
This study aimed to measure the total serum calcium and ionized calcium levels both before and after surgery. Additionally, NRS scores were recorded at different time points.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 350
- Aged 18-70 years old
- American Society of Anesthesiologists Classification I-III
- Patients undergoing elective abdominal surgery under general anesthesia
- Patients participate voluntarily and sign an informed consent form
- Patients with a history of severe disease
- Patients with chronic preoperative pain and/or long-term analgesic use
- Patients with hearing disorders or verbal communication difficulties
- Patients with psychiatric disorders or cognitive dysfunction
- Patients requiring mechanical ventilation or ICU admission after surgery
- Patients with a history of substance or alcohol abuse Patients who could not cooperate with the study for any reason
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The incidence of pain NRS score ≥6 within 48 hours after surgery From the end of the surgery to 48 hours after surgery NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively）
- Secondary Outcome Measures
Name Time Method The maximum incisional pain score at 0-12h postoperatively From the end of the surgery to 12 hours after surgery NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively）
The maximum incisional pain score at 12-24h postoperatively From 12hours to 24 hours after surgery NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively）
The maximum incisional pain score at 24-48h postoperatively From 24 hours to 48 hours after surgery NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively）
The maximum visceral pain score at 0-12h postoperatively From the end of the surgery to 12 hours after surgery NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively）
The maximum visceral pain score at 12-24h postoperatively From 12 hours to 24 hours after surgery NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively）
The maximum visceral pain score at 24-48h postoperatively From 24 hours to 48 hours after surgery NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively）
Whether additional analgesia was administered within 48 hours after surgery From the end of the surgery to 48 hours after surgery The proportion of patients who received additional analgesia out of the total patient group
Patient-controlled intravenous analgesia opioid consumption From the end of the surgery to 24 hours and 48 hours after surgery PCIA opioid consumption was assessed by checking the PCIA electronic system
Trial Locations
- Locations (1)
The Second Affiliated Hospital of Chongqing Medical University
🇨🇳Chongqing, Chongqing, China