Comparative Methods in Identifying Causative Microorganisms in Presumed Bacterial Endophthalmitis: Blood Culture System, PCR, and Conventional System
- Conditions
- yield of culture positive by 3 methods,H/C,PCR and conventionalEndophthalmitisHemoculturePCRBlood cultureConventional culture
- Registration Number
- TCTR20110000024
- Lead Sponsor
- Ratchadaphiseksomphot Endowment Fund
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 41
All cases of presumed bacterial endophthalmitis which are defined as the patients with
1.Best corrected visual acuity 20/50 or worse
2.Symptoms and signs of bacterial endophthalmitis no longer than 3 weeks: sudden visual loss, ocular pain, photophobia, red eye, A/C flare and cell, hypopyon and vitreous cell or clumping
3.In case of clinical suspect of bacterial endophthalmitis but posterior segment cannot be visualized. There must be positive finding of endophthalmitis from B-scan ultrasound
4.Etiology from recent post intraocular surgery, intraocular trauma or endogeneous infection.
All patients with
1.Suspected non-bacterial endophthalmitis
2.History of uveitis
3.Inadequate specimen for laboratory analysis
4.The patient is not performed vitreous tapping or PPV or evisceration in King Chulalongkorn memorial hospital
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the yield of detecting and identifying the causative organisms of presumed bacterial endo within 1-2 weeks after specimen collection the yield of culture positive micro organism in these 3 methods
- Secondary Outcome Measures
Name Time Method 1.To identify an incidence of presumed bacterial endophthalmitis and cultured positive endophthalmi an incidence of culture positive endhophthalmitis cases