MedPath

Enhancing Immune Health Randomized Controlled Trial

Not Applicable
Recruiting
Conditions
Mental Disorder
Interventions
Behavioral: Enhancing Your Immune Health
Registration Number
NCT05639881
Lead Sponsor
University of Illinois at Chicago
Brief Summary

This study tests a psychosocial intervention to improve immune health literacy and behaviors among adults with mental illnesses.

Detailed Description

This study is testing the efficacy of a brief intervention designed to improve immune health literacy and behaviors among adults with mental illnesses. This psychoeducational intervention supports lifestyle changes, including promotion of immunity-enhancing nutrition and immunity aids, activated intentions to receive needed inoculations and annual health screenings, better sleep, and more effective stress management. Adult clients of collaborating community mental health agencies are randomly assigned to the intervention plus services as usual, versus services as usual alone. They are assessed at baseline, two months post-baseline, and three months later. Multivariable analysis models are used to assess the primary outcome of self-reported immune status.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
100
Inclusion Criteria
  • Age 18 and older
  • Serious mental illness
  • Membership in a collaborating community mental health agency
  • Access to the Internet
  • Able to provide informed consent
Exclusion Criteria
  • Cognitive impairment preventing informed consent
  • Unable to communicate in English

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Experimental: InterventionEnhancing Your Immune HealthSubjects receive a brief intervention to improve their immune health literacy and self-management skills.
Services as UsualEnhancing Your Immune HealthSubjects receive routine mental health care.
Primary Outcome Measures
NameTimeMethod
Change in Immune Statusstudy entry (pre-intervention), immediate post-intervention, 3 months post-intervention

The Immune Status Questionnaire (ISQ) measures self-reported immune status. The questionnaire consists of 7 items measuring indicators of immune health including headache, muscle and joint pain, cough, and sudden high fever. Respondents rate each item using a 5-point Likert scale ranging from "never" to "always or almost always." Responses are coded 0-4 and summed for a total score potentially ranging from 0 to 28 with higher scores indicating a poorer immune status.

Secondary Outcome Measures
NameTimeMethod
Change in Health Promoting Lifestylestudy entry (pre-intervention), immediate post-intervention, 3 months post-intervention

The ability to engage in health promoting behaviors and practices is assessed via self-report on a 26-item Health Promoting Lifestyle Profile II scale that yields a total score and 3 subscales measuring nutrition, physical activity, and emotional and spiritual wellness.

Change in Perceived Competence for Health Managementstudy entry (pre-intervention), immediate post-intervention, 3 months post-intervention

The Perceived Competence for Health Management scale measures participants' feelings of competence about their ability to manage their immune health. This 4-item scale uses a 7-point Likert response format ranging from "not at all true" to "very true." The minimum value is 4 and the maximum is 28, with higher scores indicating a better outcome.

Change in Coping Masterystudy entry (pre-intervention), immediate post-intervention, 3 months post-intervention

Change in subjects' sense of personal control over important life outcomes is assessed via 7 items of the Coping Mastery Scale rated along a 4-point Likert scale from "strongly disagree" to "strongly agree." Higher values equal better coping mastery. Minimum=2 and maximum=49.

Trial Locations

Locations (1)

University of Illinois Chicago

🇺🇸

Chicago, Illinois, United States

© Copyright 2025. All Rights Reserved by MedPath