Therapeutic value of CT-guided periradicular and facet joint infiltrations in patients with chronic low back pain and radiculopathy
- Conditions
- M47.26M51.1Lumbar and other intervertebral disc disorders with radiculopathy
- Registration Number
- DRKS00023722
- Lead Sponsor
- niversitätsklinikum Jena
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 250
The inclusion criteria were patients aged > 18 years with predominantly lumbar back pain or predominantly monoradicular leg pain after the failure of structured non-invasive conservative treatment with pain relievers and physiotherapy for at least six weeks and a complaint duration of at least 12 weeks. In patients with predominantly unilateral lumbar radiculopathy based on an imaged-morphologically (MR-tomographically) secured monosegmental nerve root compression (caused by a herniated disc, stenosis of the lateral recess or neuroforamen), a PRI was performed. In patients with predominantly lumbar pain based on an imaged-morphologically (MR-tomographically) secured monosegmental lumbar segment degeneration (intervertebral disc degeneration, osteochondrosis, degenerative spondylolisthesis) with spondylarthrosis with Fujiwara grade >= 3 °, an FGI was performed. All patients were mentally and physically capable of declaring consent and processing the questionnaires.
Exclusion criteria were previous surgeries on the affected spine segment, multisegmental pathologies in the MRI of the lumbar spine, as well as bilateral radicular complaints. Furthermore, patients in whom the peri-interventional risk profile was increased due to other diseases were excluded. These included insufficiently controlled diabetes mellitus, intake of oral anticoagulants, clotting disorders, increased laboratory infection parameters (leukocytosis, increased CRP), and known infections and/or cancer diseases. Patients who had an absolute surgical indication due to acute serious neurological deficits (e.g. paresis > 3/5 according to Janda, conus / cauda syndrome) were also excluded from the study.
In addition, patients who could not meet the requirements for telephone interviews were excluded from the study, as were patients with a known allergy to local anesthetics (LA) or corticosteroids.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Endpoints were improvement of pain (NRS) and function (Oswestry disability Index) with regard to Minimally Clinically Important Difference (MCID) at time points: postinterventionally, 6 weeks, 3, 6, 12 months.
- Secondary Outcome Measures
Name Time Method Improvement of satisfaction (McNab) and HrQoL at 1 year.