Prophylactic antiemetic effects of Ondansetron and Haloperidol patients undergoing mastectomy- double-blind clinical trial
Phase 3
Recruiting
- Conditions
- Mastectomy surgery.
- Registration Number
- IRCT20240224061097N1
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
All candidate patients for bilateral mastectomy 2 side
ASA class 1 and 2 patients
All patients with general anesthesia
Patients aged 35-60.
Exclusion Criteria
Duration of surgery more than 150 minutes
Parkinson's disease
Patients with a history of psychiatric disorders
History of chemotherapy and radiation therapy
History of nausea and vomiting in previous surgeries
Having a movement disorder patient with a history of malignancy
Patients with prolonged QT interval
Use of opioids, sedatives, or any type of analgesic within one week before mastectomy History of alcohol consumption
History of drug abuse
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcomes of the study are the incidence of postoperative vomiting. Timepoint: The severity of nausea and vomiting of patients at the beginning of recovery and also at time intervals of 6 hours and 42 hours after surgery. Method of measurement: It will be measured by VAS.
- Secondary Outcome Measures
Name Time Method umber of times vomiting. Timepoint: At the beginning of recovery and also at time intervals of 6 hours and 42 hours after surgery. Method of measurement: It will be available to patients in recovery based on the VAS criteria.;Severity of postoperative nausea. Timepoint: At the beginning of recovery and also at time intervals of 6 hours and 42 hours after surgery. Method of measurement: The severity of nausea is collected by the number shown by the patient on the ruler.;Time of first vomiting. Timepoint: At the beginning of recovery and also at time intervals of 6 hours and 42 hours after surgery. Method of measurement: Patients who have reached the stage of vomiting are recorded.