Construction of a Precision and Individualized Management Model for Diabetes With Integrated Traditional Chinese and Western Medicine
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 2,000
- 主要终点
- Traditional Chinese Medicine Syndrome Score
研究概览
简要总结
This project will leverage a large-scale cohort of early-onset type 2 diabetes patients to conduct innovative prospective clinical research. By integrating traditional Chinese medicine diagnostic information, clinical data, laboratory results, continuous glucose monitoring, genetic information, multi-omics data, and multi-modal monitoring data, and utilizing advanced data analysis methods such as deep learning, the project aims to establish a comprehensive monitoring, precise classification, and personalized diagnosis and treatment model-a holistic management approach integrating traditional Chinese and Western medicine for early-onset type 2 diabetes. This initiative is expected to enhance the management of early-onset type 2 diabetes, improve treatment outcomes and quality of life for affected patients, pioneer an innovative path for personalized integrated traditional Chinese and Western medicine management in this population, and promote the application of precision medicine in diabetes prevention and treatment.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The age at diabetes diagnosis is ≥18 years but <40 years.
排除标准
- •The clinical diagnosis was type 1 diabetes, and at the time of enrollment, antibody levels or insulin/C-peptide results still supported the original diagnosis.
- •There were clear secondary factors contributing to hyperglycemia, such as Cushing's syndrome or pheochromocytoma.
结局指标
主要结局
Traditional Chinese Medicine Syndrome Score
时间窗: Through study completion, an average of 3 months
HbA1c
时间窗: Through study completion, an average of 3 months
次要结局
- Triglycerides(Through study completion, an average of 3 months)
- High-Density Lipoprotein Cholesterol(Through study completion, an average of 3 months)
- Total Cholesterol(Through study completion, an average of 3 months)
- Fasting Blood Glucose(Through study completion, an average of 3 months)
- Low-Density Lipoprotein Cholesterol(Through study completion, an average of 3 months)
研究者
Xinhua Xiao
Chief physician
Peking Union Medical College Hospital