Clinical Usefulness of Therapeutic Drug Monitoring of Colistin in Patients Treated With Colistin.

Not Applicable

Completed

• Conditions: Multidrug-resistant Gram-negative Bacteria Infection
• Interventions: Other: Therapeutic drug monitoring

• Registration Number: NCT03007290
• Lead Sponsor: Seoul National University Hospital

Brief Summary

Clinical usefulness of therapeutic drug monitoring of colistin in patients treated with colistin

Detailed Description

Not available

Study Timeline

• Study Start: 2016-01
• Study First Submitted: 2016-12-28
• Study First Submitted QC: 2016-12-29
• Study First Posted: 2017-01-02
• Primary Completion: 2017-12
• Study Completion: 2017-12
• Status Verified: 2018-04
• Last Update Submitted: 2018-04-16
• Last Update Posted: 2018-04-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

• Age over 18 years old.
• Those who receive colistin therapy for the treatment of multi-drug resistant gram negative bacteria infection.

Exclusion Criteria

• Those who received colistin therapy less than 48 hours
• Those who received colistin therapy through the bronchus

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Treatment group	Therapeutic drug monitoring	Group with therapeutic drug monitoring

Primary Outcome Measures

Name	Time	Method
AKI	Through study completion, an average of 1 month	Emergence rate of acute kidney injury

Secondary Outcome Measures

Name	Time	Method
Death	Through study completion, an average of 1 month	Death rate
Negative conversion rate	Through study completion, an average of 1 month	Culture-negative conversion rate Treatment success Treatment success

Trial Locations

Locations (1)

Seoul National University Bundang Hospital; 🇰🇷 Seongnam, Korea, Republic of