Evaluation of pupillometrY for External Ventricular Drains Stop

Completed

• Conditions: All Indication for External Ventricular Drain Clamping
• Interventions: Other: Electronic pupillometer analysis

• Registration Number: NCT04643717
• Lead Sponsor: Centre Hospitalier Universitaire de la Réunion

Brief Summary

Placement of an external ventricular shunt is one of the most common neurosurgical procedures in neuro-resuscitation. However, the modalities of its withdrawal are not, the subject of recommendations but rather of service habits. It has been recently demonstrated that pupillary monitoring by an electronic pupillometer was more reliable than standard clinical monitoring in brain injury patients. This tool provides access to a rich pupillary semiology at the patient's bed.

So the goal is to study the evolution of the various pupillary parameters analyzed by the electronic pupillometer during the external ventricular shunt weaning tests and to highlight the predictive factors of failure.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-11-02
• Status Verified: 2020-11
• Primary Completion: 2020-11-02
• Study Completion: 2020-11-02
• Study First Submitted: 2020-11-06
• Study First Submitted QC: 2020-11-19
• Last Update Submitted: 2020-11-19
• Study First Posted: 2020-11-25
• Last Update Posted: 2020-11-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 110

Inclusion Criteria

• All patients for whom the doctor orders an external ventricular bypass clamp test
• Neuro-injured patients and non-neuro-injured patients whose state of health requires sedation and mechanical ventilation

Exclusion Criteria

• Ophthalmological pathology making impossible to carry out measurements by the pupillometer (chemosis, eyelid edema, enucleation, etc.).
• Pregnant woman.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
intensive care patients	Electronic pupillometer analysis	-

Primary Outcome Measures

Name	Time	Method
The difference in pupillary contraction speed during the photomotor reflex measured by electronic pupillometer as a function of the outcome of the External ventricular lead clamping test	48 HOURS

Secondary Outcome Measures

Name	Time	Method
Comparison of the pupillometry parameters between neuro wronged's patients and not neuro wronged's patients (parameters measured by pupillometer)	48 HOURS

Trial Locations

Locations (2)

CHU de la Réunion; 🇫🇷 Saint-Pierre, France

Hôpital La Timone; 🇫🇷 Marseille, France