Efficacy of once daily versus divided daily administration of low daily dosage (15 mg/day) of methimazole in the induction of euthyroidism in Graves' hyperthyroidism: A randomized controlled study

Phase 4

Completed

• Conditions: Graves’ hyperthyroidism; Graves’ hyperthyroidism, once daily methimazole administration, induction of euthyroidism

• Registration Number: TCTR20170529001
• Lead Sponsor: one

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2017-03-01
• Study Start: 2017-05-29
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 55

Inclusion Criteria

Graves' hyperthyroidism was based on clinical and biochemical features including presence of signs and symptoms of thyrotoxicosis, diffuse enlargement of thyroid gland, and elevated serum free thyroid hormones accompanied with suppressed serum thyroid-stimulating hormone (TSH) levels.

Exclusion Criteria

Other causes of thyrotoxicosis

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the efficacy in the reduction of serum thyroid hormone levels before and at 2, 4, 8 and 12 weeks of the study comparing results of FT3, FT4

Secondary Outcome Measures

Name	Time	Method
/A N/A N/A