Adjunctive Use Of A Novel Hyaluronic Acid/Chlorhexidine Gel In The Non Surgical Treatment Of Periodontitis
Not Applicable
Recruiting
- Conditions
- PeriodontitisChlorhexidineHyaluronic Acid
- Interventions
- Procedure: Non surgical periodontal therapy
- Registration Number
- NCT05682833
- Lead Sponsor
- University of Sharjah
- Brief Summary
General Objective :
To evaluate the outcome of non surgical periodontal therapy with local drug delivery adjunct to scaling and root planning
Specific Objective :
To determine the effect of intra-pocket application of hyaluronic acid /chlorohexidine gel in non surgical periodontal treatment on clinical periodontal parameters and microbiological level .
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
- Age : 20-60 years old
- At least 20 remaining teeth
- Periodontitis stage III and IV ,Grade A, B and C
Exclusion Criteria
- Patients taking specific medications: antibiotic , anticoagulants or anti-inflammatory
- Previous periodontal therapy in the past 3-6 months.
- Immunocompromised patients
- Systemically diseased patients: Diabetes ,osteoporosis etc
- History of allergies or hypersensitivity reactions to chlorohexidine or Hyaluronic acid
- Pregnant or lactating women.
- Heavy Smokers (more than 20/day)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Control Non surgical periodontal therapy NS therapy + Placebo gel subgingival application Test Non surgical periodontal therapy NS therapy + Chlorhexidine/Hyaluronic acid subgingival gel application
- Primary Outcome Measures
Name Time Method Clinical attachment level 2 months pocket depth 2 months Bleeding on Probing 2 months
- Secondary Outcome Measures
Name Time Method Plaque index 2 months
Trial Locations
- Locations (1)
University Dental Hospital Sharjah
🇦🇪Sharjah, United Arab Emirates