A clinical comparative Study of Ropivacaine with Dexmedetomidine or Ropivacaine with Fentanyl as an adjuvant in Thoracic Epidural for patients undergoing abdominal surgeries.
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/01/061452
- Lead Sponsor
- Prashant Singh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
ASA physical status I and II patients undergoing elective abdominal surgeries.
1. Age less than 25 years and more than 60 years.
2. Unwilling patients not giving consent for operation.
3. Emergency cases and cases of duration more than 3 hours.
4. ASA physical status class III or more.
5. Patients having known hypersensitivity to amide local anaesthetics and Dexmedetomidine.
6. Patients displaying sign and symptoms of systemic infection.
7. Patients having local infection in thoracic spinal region.
8. Patients with pre-existing Diabetes Mellitus, Hypertension, Ischaemic Heart Disease, COPD or any other major systemic illness.
9. Pre-existing CNS disorder-Epilepsy and raised intracranial tension.
10. Pre-existing respiratory disorder-COPD, Asthma, Chronic Bronchitis.
11. Severe renal, hepatic, cardiological, haematological, metabolic disorder.
12. Cardiovascular malformation.
13. Bleeding diathesis or coagulopathy.
14. Spinal deformity.
15. Patients on anticoagulant or antiplatelet therapy.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postoperative analgesia with Duration of analgesiaTimepoint: From time of insertion of epidural and drug given till the time patient starts complaining pain.
- Secondary Outcome Measures
Name Time Method 1. Intraoperative Haemodynamic status: HR, BP (MAP), SpO2. <br/ ><br> 2. Duration of sensory block. <br/ ><br> 3. Duration of motor block. <br/ ><br>4. Time of rescue analgesia. <br/ ><br>5. Complications. <br/ ><br>Timepoint: 1. Intraoperative Haemodynamic status like HR, BP (MAP), SpO2 are measured every 1 minute for first 5 minutes, then every 5 minutes for next 15 minutes,after that every 10 minutes for next 40 minutes & lastly every 20 minutes till the end of the surgery. <br/ ><br> 2. Duration of sensory block & Duration of motor block is from drug given till patient complaint of sensation & motor power. <br/ ><br>4. Time of rescue analgesia means time when patient required any pain medication. <br/ ><br>5. Complications. <br/ ><br>