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Study of Early-stage Lung Adenocarcinoma for Early Detection and Effective Treatment Strategy

Conditions
Lung Adenocarcinoma
Interventions
Other: CT, PET, copy number alteration
Registration Number
NCT01482585
Lead Sponsor
Samsung Medical Center
Brief Summary

to determine the values of imaging and genetic biomarkers for prediction of tumor aggressiveness and prognosis in patient with early stage lung adenocarcinoma to Identify unique copy number alteration in patient with early stage lung adenocarcinoma to evaluate the long-term change of ground-glass nodule combined with lung adenocarcinoma to suggest a guideline for planning an appropriate follow-up examination and management

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
200
Inclusion Criteria
  • A. Clinically and radiologically suspected lung adenocarcinoma
  • B. Newly-diagnosed Stage I or II from the clinical work up including PET/CT
  • C. Performance status of 0 to 1 on the ECOG scale
  • D. Age 20 years or older
  • E. Able to tolerable DECT imaging required by protocol
  • F. Able to give study-specific informed consent
Exclusion Criteria
  • A. Prior malignancy
  • B. planning of Definitive RTx 나 neoadjuvant CCRTx
  • C. Poor cardiopulmonary reserve

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
early stage lung adenocarcinomaCT, PET, copy number alteration-
Primary Outcome Measures
NameTimeMethod
Prediction of tumor aggressivenessfive years
Secondary Outcome Measures
NameTimeMethod
prognosis of early stage lung adenocarcinoma following operationfive years

Trial Locations

Locations (1)

Samsung Medical Center

🇰🇷

Seoul, Korea, Republic of

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