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Clinical Trials/NCT03650179
NCT03650179CompletedNot Applicable

Influence of the Urine Stream Interruption Exercise on the Micturition

Pierre and Marie Curie University1 site in 1 country20 target enrollmentStarted: August 23, 2018Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
20
Locations
1
Primary Endpoint
post-void residual volume

Study Overview

Brief Summary

This study assess micturition characteristic during and after a urine stream interruption exercise in patient without neurological or urologic disease.

Detailed Description

Urine stream interruption during voluntary voiding is often performed by women as a pelvic floor muscle exercise to develop urinary strength and avoid urinary incontinence. To our knowledge, there is no recommendation for performing urine stream interruption. Without evidence based data, stooping the urinary flow is reported as a risk of post void residual and urinary infection. The experts did not recommended to practice urine stream interruption as a pelvic floor exercise in urinary incontinence. However, during pelvic floor muscle training for urinary incontinence, exercises of urine stream interruption are often performed without knowledge of their consequences. The aim of this study is to assess micturition characteristic during and after a urine stream interruption exercise.

In this study, the investigators will compare the two uroflowmetries usually done in a Neuro-urology department of a University Hospital. Patient without neurological or urologic disease, consulting for a global evaluation of functional digestive disease and performing an urodynamic study will be included. During the urodynamic evaluation, two uroflowmetries are performed : one conventional uroflowmetry complying with the International Continence Society (ICS) recommendations and one uroflowmetry during exercise of urine stream interruption, as usually done in the department. Each uroflowmetry will be performed when the patient will feel a ''normal'' desire to void. For the urine stream interruption micturition, patients will be asked to "begin the micturition, stop at 3 seconds of micturition, when the stream is interrupt, start again voiding, again stop at 3 seconds of micturition and repeat this maneuver until the end of the micturition". As usual, sonographic estimation of post-void residual volume will complete each uroflowmetry.

The investigators will compare the voiding volume, the post-void residual volume, the maximal flow rate, the time to reach the maximal flow rate, the voiding time and the slope of the uroflowmetry (corresponding to the flow velocity acceleration) between the two uroflowmetries. For each voiding sequence of the urine stream interruption micturition the following parameters will be reported and compared: voiding volume and duration, maximal flow rate, time to reach the maximal flow rate, the latency to restart the micturition between each voiding sequence and the slope of the uroflowmetry.

Statistical analysis will be carried out using R 3.2.3 software (R Development Core Team, http://www.R-project.org) and R studio version 1.0.136. Differences between the two uroflowmetries will be evaluated using Student test. Correlation between the place of the voiding sequence in the urine stream interruption micturition and the different parameters will be evaluated using Pearson's correlations.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
Female
Accepts Healthy Volunteers
No

Inclusion Criteria

  • follow in neuro-urology for functional digestive disease
  • Appointment for urodynamic assessment

Exclusion Criteria

  • urological or neurological disease

Outcomes

Primary Outcomes

post-void residual volume

Time Frame: 1 Day : during the urodynamic assessment

comparison between post-void residual volume during normal micturition and exercise of urine stream interruption

Secondary Outcomes

  • the slope of the uroflowmetry (corresponding to the flow velocity acceleration)(1 Day : during the urodynamic assessment)
  • voiding time(1 Day : during the urodynamic assessment)
  • maximal flow rate(1 Day : during the urodynamic assessment)
  • time to reach the maximal flow rate(1 Day : during the urodynamic assessment)

Investigators

Sponsor
Pierre and Marie Curie University
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Gérard Amarenco

Head of Neuro-urology department, Tenon hospital

Pierre and Marie Curie University

Study Sites (1)

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