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Evaluation of a new surgical technique in neuroendocrine tumors

Phase 1
Conditions
Gastro-entero-pancreatic neuroendocrine tumors
MedDRA version: 20.0Level: PTClassification code 10057270Term: Neuroendocrine carcinomaSystem Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Therapeutic area: Diseases [C] - Cancer [C04]
Registration Number
EUCTR2015-005202-10-IT
Lead Sponsor
ISTITUTO EUROPEO DI ONCOLOGIA
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
5
Inclusion Criteria

a) Patients of both sexes aged over 18 years
b) Patients with histologically documented diagnosis of GEP-NET candidates for surgery R0 or R2.
c) Presence of a PET / CT with 68Ga-DOTATOC showing a significant uptake (> than the liver) of the tracer at the tumor (SSR-positive)
d) Functionality marrow, liver, kidney and heart check with instrumental tests (ECG) and laboratory (blood count, creatinine, transaminases, gamma-GT, alkaline phosphatase, sodium and potassium)
e) Signed informed consent
f) a negative pregnancy test (blood dosage of beta HCG) not older than 7 days is required in women in premenopausal status

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 4
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 1

Exclusion Criteria

a) Patient history of malignant tumors with treatment ongoing except for basal cell carcinoma in situ and cervical cancer radically removed
b) Known intolerance to medical contrast medium and / or previous anaphylactic shock
c) Women who are pregnant or nursing, GEP-NET recurrence and considered inoperable

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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