Evaluation of Hyaluronic Matrix, Used With Xenograft, Efficacy in Sinus Augmentation by Histomorphometry and Micro Computed Tomography
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 13
- 主要终点
- Percentage of newly formed bone calculated from bone biopsises by Micro-CT and Histomorphometry
研究概览
简要总结
Sinus augmentation is a predictable method when alveolar bone height is not sufficient for dental implant placement in posterior maxillary alveolar region..The aim of this prospective, randomized, controlled clinical study is comparison of hyaluronic acid originated matrix and equine derived xenograft with only xenograft use in sinus augmentation by micro computed tomography and histomorphometry.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 33 Years 至 69 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Systemically healthy patients
- •Requiring bilateral maxillary sinus augmentation (residual crest height ≤ 4 mm)
排除标准
- •Advanced systemic diseases
- •Chronic medication use
- •Maxillary sinus disease
- •Current pregnancy
- •Lactation
- •Smoking habit
研究组 & 干预措施
Hyalossᵀᴹ matrix
Each 0.5 cc Collagenated Heterolog Bone Graft, mixed with two bundles of Hyalossᵀᴹ matrix and a few drops of sterile saline solution used for maxillary sinus augmentation
干预措施: Maxillary Sinus Augmentation (Procedure)
Apatos alone xenograft
Each sinus was filled with 1 gr xenograft (with or without Hyaluronic Acide) for maxillary sinus augmentation
干预措施: Maxillary Sinus Augmentation (Procedure)
结局指标
主要结局
Percentage of newly formed bone calculated from bone biopsises by Micro-CT and Histomorphometry
时间窗: 4 months after surgery
Biological parameter obtained by analyzing bone biopsises
次要结局
未报告次要终点
研究者
EZGİ DOĞAN
Principal Investigator
Hacettepe University