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临床试验/ISRCTN14167992
ISRCTN14167992
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Aerobic exercise to improve cardiopulmonary function in people with Parkinson’s: a mixed-methods pilot study

Keele University0 个研究点目标入组 21 人2019年3月18日

概览

阶段
未知
干预措施
未指定
疾病 / 适应症
未指定
发起方
Keele University
入组人数
21
状态
已完成
最后更新
2年前

概览

简要总结

暂无简介。

注册库
who.int
开始日期
2019年3月18日
结束日期
2021年1月1日
最后更新
2年前
研究类型
Interventional
性别
All

研究者

入排标准

入选标准

  • 1\. Adults (male and female) aged over 18 years old, diagnosed with Parkinson’s according to the UK Brain Bank Criteria.
  • 2\. Disease severity classified between I\-III according to the Hoehn and Yahr scale. Patients with I\-III scores on Hoehn and Yahr are able to walk independently without assistance. Participants will be requested to do a sub\-maximal CPET, therefore they need to be walking independently.
  • 3\. Ability to stand and walk for at least 10 meters without assistance.
  • 4\. Ability to understand instructions, with Mini\-Mental State Examination score (MMSE) \=24 (scores \<24 reflect cognitive impairment).

排除标准

  • 1\. Pre\-existing diagnosis of lung disease, e.g. chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis, emphysema, lung cancer.
  • 2\. Current smoker.
  • 3\. Participants with a history of heart disease that would present a risk of adverse cardiac event in response to the sub\-maximal exercise tests (in accordance with the American Heart Association/ American College of Sport Medicine guidelines) as identified using the American Heart Association/ American College of Sport Medicine (AHA/ACSM) Health/Fitness Facility Pre\-Participation Questionnaire.
  • 4\. Any other previously diagnosed musculoskeletal or neurological disorder that may prevent participation in physical activity.
  • 5\. Inability to understand English language (for the purpose of understanding instructions and information related to the study, as no interpreter is available).
  • 6\. Participants are required to sign a consent form, understand the instructions of the tests, the interventions and answer questionnaires. Thus, participants will be excluded from the study if they have dementia (as indicated by a MMSE score \<24\), or any other neurological or psychiatric disorder that would mean participants were unable to provide written informed consent.

结局指标

主要结局

未指定

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