NCT03584607已完成不适用
Insulin- and Glucose Metabolism in Pulmonary Arterial Hypertension - a Pilot Study
Medical University of Graz1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2017年12月20日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Insulin resistance
研究概览
简要总结
Insulin resistance is a key mechanism in metabolic disorders, which has also been implicated in the development of pulmonary hypertension. In this pilot study, the investigators´ goal is to directly determine insulin sensitivity in idiopathic pulmonary arterial hypertension patients and to compare the results with data from healthy controls.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •signed informed consent form
- •patients with idiopathic or hereditary pulmonary hypertension / healthy controls
排除标准
- •premenopausal women
- •other relevant lung disease
- •relevant left heart disease
- •untreated systemic hypertension
- •Diabetes mellitus
- •pulmonary hypertension other than idiopathic or hereditary form
结局指标
主要结局
Insulin resistance
时间窗: 1 day
Determination of insulin sensitivity using hyperinsulinemic-euglycemic clamp technique
次要结局
未报告次要终点
研究者
研究点 (1)
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