Music Therapy and Bio-psychological Effect Among Chronic Psychiatric Inpatients of a Community Teaching Hospital

Not Applicable

• Conditions: Chronic Psychosis
• Interventions: Other: Music therapy; Device: Biosignal analysis

• Registration Number: NCT04254965
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

Negative symptoms are an important factor in preventing patients from returning to the community, we aim to assess the effect of music therapy on negative symptoms through this study. Participants of integrated music therapy will receive instrument playing, singing, lyrics modification/music organized play, listening to music and discussing each treatment process. Other participants will receive passive music listening or regular occupational therapy during the experimental period. Psychiatric symptoms, quality of life, social and interactive skills, and the differences in the physiological signals produced by skin, muscles, and heart will be measured before, after, and two months after the music therapy.

Detailed Description

Music therapy is gradually being used in the field of psychiatry, such as depression, anxiety, and development disorders in children. However, music therapy still lacks systematic research on chronic mental illness. Since negative symptoms are an important factor in preventing patients from returning to the community, we aim to assess the effect of music therapy on negative symptoms through this study. Additionally, Taiwan as many Asian countries have not yet established a certification system for music therapy. This study cooperates with licensed therapists abroad in the hope of promoting the systematic development of local music therapy in the future.

Participants of integrated music therapy (Group 1, integration of active and passive music therapy) includes instrument playing, singing, lyrics modification/music organized play, listening to music and discussing each treatment process. The four stages of activities are warm-up, main activities, secondary activities, and the ending section. The participants of the music listening group (Group 2, background music listening), music selection based on the musical preference and background of subjects, for relax or boost the spirit of the subjects. Participants in the control group (Group 3) receive their regular occupational therapy during the experimental period. We plan to recruit 100 people in the wards: 40/20/40 (Group 1/2/3) under random assignment.

To evaluate the effects of three groups, we measure their psychiatric symptoms, quality of life, social and interactive skills, and the differences in the physiological signals produced by skin, muscles, and heart assisted by a medical engineering scholar before, after, and two months after the music therapy.

Study Timeline

• Study First Submitted: 2020-01-05
• Status Verified: 2020-02
• Study Start: 2020-02
• Study First Submitted QC: 2020-02-02
• Study First Posted: 2020-02-05
• Last Update Submitted: 2020-02-06
• Last Update Posted: 2020-02-10
• Primary Completion: 2020-12
• Study Completion: 2020-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Not provided

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Exclusion Criteria

Not provided

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
Group 1	Music therapy	Participants of integrated music therapy (integration of active and passive music therapy) includes instrument playing, singing, lyrics modification/music organized play, listening to music and discussing each treatment process. The four stages of activities are warm-up, main activities, secondary activities, and the ending section.
Group 1	Biosignal analysis	Participants of integrated music therapy (integration of active and passive music therapy) includes instrument playing, singing, lyrics modification/music organized play, listening to music and discussing each treatment process. The four stages of activities are warm-up, main activities, secondary activities, and the ending section.
Group 2	Music therapy	Participants of the music listening group will receive background music listening, music selection based on the musical preference and background of subjects, for relax or boost the spirit of the subjects.
Group 2	Biosignal analysis	Participants of the music listening group will receive background music listening, music selection based on the musical preference and background of subjects, for relax or boost the spirit of the subjects.
Group 3	Biosignal analysis	Participants in the control group receive their regular occupational therapy during the experimental period.

Primary Outcome Measures

Name	Time	Method
Change of social and interactive skills	Before and 2 months after finishing the music therapy	Using the Assessment of Communication and Interaction Skills scale (in Traditional Chinese)
Change of negative symptoms of inpatients with psychotic disorders	Before and 2 months after finishing the music therapy	Using the Scale for the Assessment of Negative Symptoms (in Traditional Chinese)
Change of quality of life	Before and 2 months after finishing the music therapy	Using the World Health Organization Quality of Life-BREF questionnaire (it is a compress name, Traditional Chinese version). The WHOQOL-BREF was derived from data collected using the WHOQOL-100. It produces scores for four domains related to quality of life: physical health, psychological, social relationships and environment. It also includes one facet on overall quality of life and general health. Potential scores for all domain scores range from 4(worse) to 20(better).

Secondary Outcome Measures

Name	Time	Method
Change of facial expression by action landmarks	Two months	To evaluate emotion (e.g. anger, fear, disgust, contempt, sadness, and surprise) via facial motion by iMotions device
Heart Rate Variability in Psychiatric Disorders analysis	Two months	Measure Heartbeat variability after intervention activities by "Dailycare" CheckMyHeart
Sleep schedule	Two months	Recorded by Fitbit health watch, meaning the hours patients are asleep
Total sleeping time	Two months	Recorded by Fitbit health watch
Motion analysis	Two months	Analysis of the electromyography (EMG) of cases recorded by DELYSYS, EMG potentials range between less than 50 μV and up to 30 mV.
Sleep pattern	Two months	Recorded by Fitbit health watch, meaning the distribution of sleep stages (light sleep, deep sleep and rapid eye movement sleep).

Trial Locations

Locations (1)

National Taiwan University Hospital; 🇨🇳 Hsinchu, Hsinchu County, Taiwan