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The early predictive factors of hypocalcemia in patients undergoing total thyroidectomy or completion thyroidectomy.

Not Applicable
Conditions
Health Condition 1: C73- Malignant neoplasm of thyroid gland
Registration Number
CTRI/2021/08/035393
Lead Sponsor
AIIMS New Delhi
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Patient planned for total thyroidectomy with or without neck dissection.

Patient giving consent to participate in study.

Patient planned for completion thyroidectomy.

Exclusion Criteria

Patient who is not willing to participate in the study

Patient is unfit for surgery under general anesthesia.

Patient having inoperable primary disease of thyroid.

Patient having secondary hypoparathyroidism

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To evaluate the role of absolute iPTH decline and absolute serum ionised calcium decline at 1 hour and 1 day post thyroidectomy in predicting hypocalcemia. <br/ ><br> <br/ ><br>To evaluate the role of serum magnesium levels in post-thyroidectomy hypocalcemia <br/ ><br>Timepoint: To evaluate the role of absolute iPTH decline and absolute serum ionised calcium decline at 1 hour and 1 day post thyroidectomy in predicting hypocalcemia. <br/ ><br> <br/ ><br>To evaluate the role of serum magnesium levels in post-thyroidectomy hypocalcemia <br/ ><br>
Secondary Outcome Measures
NameTimeMethod
To develop a composite scoring system for predicting patients at high risk for developing significant hypocalcemia in post-operative period <br/ ><br> <br/ ><br>To develop a protocol for initiating calcium and vitamin D supplementation based on biochemical results. <br/ ><br> <br/ ><br>To correlate Bethesda scoring system for thyroid cytopathology and TI-RADS system for thyroid lesion with histopathology <br/ ><br>Timepoint: At post operative day 0 and 1
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