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Feasibility of electrical mapping and stimulation of renal arteries in patients undergoing renal denervatio

Recruiting
Registration Number
NL-OMON28437
Lead Sponsor
Department of Cardiology, Isala
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
40
Inclusion Criteria

Patients with refractory hypertension and patients with combined hypertension and paroxysmal or persistent atrial fibrillation.

- Age 18-80 years

Exclusion Criteria

- Type 1 diabetes mellitus

- Contraindication to chronic anticoagulation therapy or heparin.

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Main study parameter will be the arterial blood pressure response to renal nerve stimulation (RNS) prior to renal denervation (RDN) and absence of blood pressure rise in response to pacing in the renal artery after renal denervation (RDN). <br>
Secondary Outcome Measures
NameTimeMethod
Blood pressure at 3, 6, 12 months after the intervention, and change in blood pressure compared to measurement before the intervention <br>
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