The effect of cryoprecipitate and fibrinogen concentrate for treating postpartum hemorrhage: a descriptive study - Descriptive comparison of cryoprecipitate and fibrinogen concentrate for treating PPH

Critical bleeding was declared and fibrinogen replacement therapy was performed in 25 patients. Blood loss was group C (median 3197 g) < group F (3243 g) < group CF (5704 g). Estimated total fibrinogen replacement by fibrinogen concentrates was group C (median 879 mg) < group F (3000 mg) < group CF (3842 mg). Fibrinogen levels were measured in all patients before fibrinogen replacement therapy, and all but three patients in group F had fibrinogen levels below 200 mg/dL.