Pilot study: Respiratory microbiome analysis by the IS-pro technology.
Completed
- Conditions
- COPD, bacteria, virusesCOPD, bacteriën, virussen
- Registration Number
- NL-OMON19937
- Lead Sponsor
- azM
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
In order to be eligible to participate in the study, a patient must meet all of the following criteria:
• Diagnosis of COPD stages I-IV, class A-D, as defined by the Global initiative for chronic Obstructive Lung Disease (GOLD)23;
Exclusion Criteria
A patient who meets any of the following criteria will be excluded from participation in this study:
• Chronic use of oral corticosteroids > 10 mg/day;
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine the optimal sample type for respiratory microbiome analysis using the IS-pro technology.
- Secondary Outcome Measures
Name Time Method 1. Intra-patient analysis to define and compare the respiratory microbiome and its microbial diversity by BAL fluid, bronchial aspirate, induced sputum samples, throat and nose swabs;<br /><br>2. Longitudinal analysis of respiratory microbiome in sputum, throat and nose swabs, to assess the respiratory microbiome and the microbial diversity of patients over time, between the same and different sample types.